Publications

2023


• K. Bhandari, Y. Wei, B.R. Amer, E.M. Pelegri-O'Day, J. Huh, and J.D. Schmit “Prediction of Antibody Viscosity from Dilute Solution Measurements”, Antibodies, 12, 78 (2023) Link
• N. Sabri, M. J. Cuneo, M. R. Marzahn, J. Lee, J. J. Bouchard, S. Vaithiyalingam, M.B. Borgia, J. D. Schmit, and T. Mittag “Reduction of oligomer size modulates the competition between cluster formation and phase separation of the tumor suppressor SPOP”, J. Biol. Chem, 299, 105427 (2023) Link
• J.D. Schmit and M. Dundr, “News and Views: Keeping membraneless organelles apart", Nature Cell Biology, 25, 1566-1567 (2023) Link
• S.K.K. Galagedera, T.P. Dao, S.E. Enos, A. Chaudhuri, J.D. Schmit and C.A. Castañeda, “Polyubiquitin ligand-induced phase transitions are optimized by spacing between ubiquitin units”, Proc. Nat. Acad. Sci., 120 (42) e2306638120 (2023) Link
• J.I. Ahn, L. Zhang, H. Ravishankar, L. Fan, K. Kirsch, Y. Zeng, L. Meng, J.-E. Park, H.-Y. Yun, R. Ghirlando, B. Ma, D. Ball, B. Ku, R. Nussinov, J. D. Schmit, W. F. Heinz, S. J. Kim, Tatiana K., Y.-X. Wang, and K. S. Lee, “Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells”, Comm. Biol., 6, 712 (2023) Link
• I. Horvath, H. Welte, J.D. Schmit, M. Kovermann, and P. Wittung-Stafshede, “Distinct growth regimes of alpha-synuclein amyloid elongation”, Biophys. J., 122, 2556-2563 (2023) Link
• J. D. Schmit, and K. A. Dill, “Next-Gen Biophysics: Look to the Forest, Beyond the Trees”, Ann. Rev. Biophys., 52, v-viii (2023) Link
• B. Scalvini, V. Sheikhhassani, N. van de Brug, L. W. H. J. Heling, J. D. Schmit, and A. Mashaghi, “Circuit Topology Approach for the Comparative Analysis of Intrinsically Disordered Proteins”, J. Chem. Inf. Model., 63, 2586-2602 (2023) Link
• T.T.M. Phan, T.M. Phan, and J.D. Schmit, “Beneficial and detrimental effects of non-specific binding during DNA hybridization”, Biophys. J., 122, 835-848 (2023) Link
• N. Erkamp, T. Sneideris, H. Ausserwöger, D. Qian, S. Qamar, J. Nixon-Abell, P. St George-Hyslop, J. Schmit, D. Weitz, and T. Knowles, “Spatially non-uniform condensates emerge from dynamically arrested phase separation”, Nature Comm., 14, 684 (2023) Link

2022


• S. Whitelam and J.D. Schmit, “Low-dissipation self-assembly protocols of active sticky particles”, J Cryst. Growth, 600 126912 (2022) Link
• T.M. Phan and J.D. Schmit, “Conformational entropy limits the transition from nucleation to elongation in amyloid aggregation”, Biophys. J., 121, 2931-2939 (2022) Link

2021


• J.D. Schmit, M. Feric, and M. Dundr, “How Hierarchical Interactions Make Membraneless Organelles Tick Like Clockwork", Trends Biochem. Sci. 46, 525-534 (2021) Link
• K. Bhandari, M.A. Cotten, J. Kim, M.K. Rosen, and J.D. Schmit, “Structure–Function Properties in Disordered Condensates", J. Phys. Chem. B 125, 467–476 (2021) Link bioRxiv
  2020
  
  
• T.T.M. Phan and J.D. Schmit, “Thermodynamics of Huntingtin Aggregation", Biophys. J., 118, 2989–2996 (2020) Link bioRxiv
• Z. Jia, J. D. Schmit, and J. Chen, “Amyloid assembly is dominated by misregistered kinetic traps on an unbiased energy landscape”, Proc. Nat. Acad. Sci., 117, 10322-10328 (2020) Link bioRxiv PubMed
• J. D. Schmit, J. J. Bouchard, E. W. Martin, and T. Mittag, “Protein network structure enables switching between liquid and gel states”, J. Am. Chem. Soc., 142, 874-883 (2020) Link bioRxiv PubMed

2019


• T.M. Phan, S. Whitelam, and J.D. Schmit, “Catalystlike role of impurities in speeding layer-by-layer growth”, Phys. Rev. E 100, 042114 (2019) Link
• S.S. Hopkins, A. Chakrabarti, and J.D. Schmit, “Effects of non-pairwise repulsion on nanoparticle assembly”, J. Chem. Phys. 151, 034901 (2019) PDF Link PubMed
• N. Ramallo, S. Paudel, and J.D. Schmit, “Cluster Formation and Entanglement in the Rheology of Antibody Solutions”, J. Phys. Chem. B 123, 3916-3923 (2019) Link
  2018
  
  
• J.D. Schmit, N.L. Kariyawasam, V. Needham, and P.E. Smith, “SLTCAP: A simple method for calculating the number of ions needed for MD simulation”, J. Chem. Theory Comput. 14, 4, 1823-1827 (2018) Link PubMed
• C. Huang, E. Ghanati, and J.D. Schmit, “Theory of Sequence Effects in Amyloid Aggregation”, J. Phys. Chem. B 122, 5567-5578 (2018) Link PubMed
• Y.R. Dahal and J.D. Schmit, “Ion Specificity and Nonmonotonic Protein Solubility from Salt Entropy”, Biophys. J 114, 76-87 (2018) Link PubMed

2017


• Z. Jia, A. Beugelskijk, J. Chen, and J.D. Schmit, “The Levinthal Problem in Amyloid Aggregation: Sampling of a Flat Reaction Space”, J. Phys. Chem. B 121, 1576-1586 (2017) Link PubMed
• L. Zhang and J.D. Schmit, “Theory of Amyloid Fibril Nucleation from Folded Proteins”, Israel J. Chem. 57, 738-749 (2017) Link PubMed

2016


• L. Zhang and J.D. Schmit, “Pseudo-one-dimensional nucleation in dilute polymer solutions”, Phys. Rev. E Rapid Communication 93, 060401(R) (2016) PDF Link PubMed
• S. Whitelam, Y.R. Dahal, and J.D. Schmit, “Minimal physical requirements for crystal growth self-poisoning”, J. Chem. Phys. 144, 064903 (2016) PDF Link PubMed

2012-2015


• T. Miti, M. Mulaj, J.D. Schmit, and M. Muschol, “Stable, Metastable, and Kinetically Trapped Amyloid Aggregate Phases”, Biomacromolecules, 16, 326-335 (2015). Link PubMed
• J.D. Schmit, F. He, S. Mishra, R.R. Ketchem, C.E. Woods, and B.A. Kerwin, “Entanglement model of antibody viscosity”, J. Phys. Chem. B, 118, 5044-5049 (2014) Link
• S. Whitelam, L.O. Hedges, and J.D. Schmit, “Self-assembly at a nonequilibrium critical point”, Phys. Rev. Lett. 112, 155504 (2014) PDF Link
• N. Duff, Y.R. Dahal, J.D. Schmit, and B. Peters, “Salting out the polar polymorph: Analysis by alchemical solvent transformation, J. Chem. Phys. 140, 014501 (2014) PDF Link
• J.D. Schmit, “Kinetic theory of amyloid fibril templating”, J. Chem. Phys. 138, 185102 (2013) PDF Link
• L.R. Nemzer, B.N. Flanders, J.D. Schmit, A. Chakrabarti, and C.M. Sorensen, “Ethanol shock and lysozyme aggregation”, Soft Matter 9, 2187-2196 (2013) PDF Link

2010-2012


• J. D. Schmit and K. Dill, “Growth rates of protein crystals”, J. Am. Chem. Soc. 134(9), 3934–3937 (2012) PDF Link Supplement
PubMed
• L. O. Narhi, J. Schmit, K. Bechtold-Peters, and D. Sharma, “Classification of protein aggregates”, J. Pharm. Sci. 101(2), 493-498 (2012) Link PubMed
• K. A. Dill, K. Ghosh, and J. D. Schmit, “Reply to Vazquez: Optimal density is robust to variations in calculation”, Proc. Nat. Acad. Sci. 109, E534 (2012) Link PubMed
• K. A. Dill, K. Ghosh, and J. D. Schmit, “Physical limits of cells and proteomes”, Proc. Nat. Acad. Sci. 108, 17876-17882 (2011) PDF Link PubMed
• J. D. Schmit, S. Whitelam, and K. Dill, “Electrostatics and aggregation: how charge can turn a crystal into a gel”, J. Chem. Phys. 135, 085103 (2011) PDF Link arXiv PubMed
• J. D. Schmit, K. Ghosh, and K. Dill, “Why do amyloid molecules assemble into oligomers and fibrils?”, Biophys. J. 100, 450-458 (2011) Link arXiv PubMed
• J. D. Schmit and K. Dill, “The stabilities of protein crystals”, J. Phys. Chem. B 114, 4020-4027 (2010) PDF Link PubMed Supplement

pre-2010


• J. D. Schmit, E. Kamber, and J. Kondev, “Lattice Model of Diffusion-Limited Bimolecular Chemical Reactions in Confined Environments”, Phys. Rev. Lett. 102, 218302 (2009) PDF Link arXiv
• J. D. Schmit and A. J. Levine, “Statistical Model for Intermolecular Adhesion in Conjugated Polymers”, Phys. Rev. Lett. 100, 198303 (2008) PDF Link arXiv
• A. Rahmanisisan, C. Castelnovo, J. D. Schmit, and C. Chamon, "Dynamics of single polymers under extreme confinement", J. Stat. Mech. 9, P09022 (2007) Link arXiv
• J. D. Schmit and A. J. Levine, “Intermolecular adhesion in conducting polymers”, Phys. Rev. E 71, 051802 (2005) PDF Link arXiv
• J. Schmit, R. Menes, and P.A. Pincus, “Dielectric-induced counterion partitioning and its effect on membrane rigidity”, Phys. Rev. E 66, 061502 (2002) PDF Link

articles by Jeremy Schmit on the arXiv
articles by Jeremy Schmit on the ChemRxiv
articles by Jeremy Schmit on the bioRxiv