Publications
2025
- S.A. Akram, T. Brown, S. Whitelam, G. Meisl, T.P.J. Knowles, and J.D. Schmit, “Competing addition processed give distinct growth regimes in the assembly of 1D filaments”, Biophys. J. 124, 778-788 (2025)
Link
- J.A. Larsen, A. Barclay, N. Vettore, L.K. Klausen, L.N. Mangels, A. Coden, J.D. Schmit, K. Lindorff-Larsen, and A.K. Buell, “The mechanism of amyloid fibril growth from Phi-value analysis”, Nature Chemistry, 17, 403-411 (2025)
Link
2024
- D.M. Arvelo, J. Comer, J.D. Schmit, and Ricardo Garcia, “Interfacial Water Is Separated from a Hydrophobic Silica Surface by a Gap of 1.2 nm”, ACS Nano, 18, 28, 18683–18692 (2024)
Link
- J.D. Schmit and T.C.T. Michaels “Physical limits to acceleration of enzymatic reactions inside phase-separated compartments”, Phys. Rev. E, 109, 064401
(2024)
Link
- C.C. Correll, U. Rudloff, J.D. Schmit, D.A. Ball, T.S. Karpova, E. Balzer and M. Dundr “Crossing boundaries of light microscopy resolution discerns novel assemblies in the nucleolus”, Histochemistry and Cell Biology, 162, 161-183
(2024)
Link
2023
- K. Bhandari, Y. Wei, B.R. Amer, E.M. Pelegri-O'Day, J. Huh, and J.D. Schmit “Prediction of Antibody Viscosity from Dilute Solution Measurements”, Antibodies, 12, 78
(2023)
Link
- N. Sabri, M. J. Cuneo, M. R. Marzahn, J. Lee, J. J. Bouchard, S. Vaithiyalingam, M.B. Borgia, J. D. Schmit, and T. Mittag “Reduction of oligomer size modulates the competition between cluster formation and phase separation of the tumor suppressor SPOP”, J. Biol. Chem, 299, 105427
(2023)
Link
- J.D. Schmit and M. Dundr, “News and Views: Keeping membraneless organelles apart", Nature Cell Biology, 25, 1566-1567
(2023)
Link
- S.K.K. Galagedera, T.P. Dao, S.E. Enos, A. Chaudhuri, J.D. Schmit and C.A. Castañeda, “Polyubiquitin ligand-induced phase transitions are optimized by spacing between ubiquitin units”, Proc. Nat. Acad. Sci., 120 (42) e2306638120
(2023)
Link
- J.I. Ahn, L. Zhang, H. Ravishankar, L. Fan, K. Kirsch, Y. Zeng, L. Meng, J.-E. Park, H.-Y. Yun, R. Ghirlando, B. Ma, D. Ball, B. Ku, R. Nussinov, J. D. Schmit, W. F. Heinz, S. J. Kim, Tatiana K., Y.-X. Wang, and K. S. Lee, “Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells”, Comm. Biol., 6, 712 (2023)
Link
- I. Horvath, H. Welte, J.D. Schmit, M. Kovermann, and P. Wittung-Stafshede, “Distinct growth regimes of alpha-synuclein amyloid elongation”, Biophys. J., 122, 2556-2563 (2023)
Link
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J. D. Schmit, and K. A. Dill, “Next-Gen Biophysics: Look to the Forest, Beyond the Trees”, Ann. Rev. Biophys., 52, v-viii (2023)
Link
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B. Scalvini, V. Sheikhhassani, N. van de Brug, L. W. H. J. Heling, J. D. Schmit, and A. Mashaghi, “Circuit Topology Approach for the Comparative Analysis of Intrinsically Disordered Proteins”, J. Chem. Inf. Model., 63, 2586-2602 (2023)
Link
- T.T.M. Phan, T.M. Phan, and J.D. Schmit, “Beneficial and detrimental effects of non-specific binding during DNA hybridization”, Biophys. J., 122, 835-848 (2023)
Link
- N. Erkamp, T. Sneideris, H. Ausserwöger, D. Qian, S. Qamar, J. Nixon-Abell, P. St George-Hyslop, J. Schmit, D. Weitz, and T. Knowles, “Spatially non-uniform condensates emerge from dynamically arrested phase separation”, Nature Comm., 14, 684 (2023)
Link
2022
- S. Whitelam and J.D. Schmit, “Low-dissipation self-assembly protocols of active sticky particles”, J Cryst. Growth, 600 126912 (2022)
Link
- T.M. Phan and J.D. Schmit, “Conformational entropy limits the transition from nucleation to elongation in amyloid aggregation”, Biophys. J., 121, 2931-2939 (2022)
Link
2021
- J.D. Schmit, M. Feric, and M. Dundr, “How Hierarchical Interactions Make Membraneless Organelles Tick Like Clockwork", Trends Biochem. Sci. 46, 525-534 (2021)
Link
- K. Bhandari, M.A. Cotten, J. Kim, M.K. Rosen, and J.D. Schmit, “Structure–Function Properties in Disordered Condensates", J. Phys. Chem. B 125, 467–476 (2021)
Link
bioRxiv
2020
- T.T.M. Phan and J.D. Schmit, “Thermodynamics of Huntingtin Aggregation", Biophys. J., 118, 2989–2996 (2020)
Link
bioRxiv
- Z. Jia, J. D. Schmit, and J. Chen, “Amyloid assembly is dominated by misregistered kinetic traps on an unbiased energy landscape”, Proc. Nat. Acad. Sci., 117, 10322-10328 (2020)
Link
bioRxiv
PubMed
- J. D. Schmit, J. J. Bouchard, E. W. Martin, and T. Mittag, “Protein network structure enables switching between liquid and gel states”, J. Am. Chem. Soc., 142, 874-883 (2020)
Link
bioRxiv
PubMed
2019
- T.M. Phan, S. Whitelam, and J.D. Schmit, “Catalystlike role of impurities in speeding layer-by-layer growth”, Phys. Rev. E 100, 042114 (2019)
Link
- S.S. Hopkins, A. Chakrabarti, and J.D. Schmit, “Effects of non-pairwise repulsion on nanoparticle assembly”, J. Chem. Phys. 151, 034901 (2019)
PDF
Link
PubMed
- N. Ramallo, S. Paudel, and J.D. Schmit, “Cluster Formation and Entanglement in the Rheology of Antibody Solutions”, J. Phys. Chem. B 123, 3916-3923 (2019)
Link
2018
- J.D. Schmit, N.L. Kariyawasam, V. Needham, and P.E. Smith, “SLTCAP: A simple method for calculating the number of ions needed for MD simulation”, J. Chem. Theory Comput. 14, 4, 1823-1827 (2018)
Link
PubMed
- C. Huang, E. Ghanati, and J.D. Schmit, “Theory of Sequence Effects in Amyloid Aggregation”, J. Phys. Chem. B 122, 5567-5578 (2018)
Link
PubMed
- Y.R. Dahal and J.D. Schmit, “Ion Specificity and Nonmonotonic Protein Solubility from Salt Entropy”, Biophys. J 114, 76-87 (2018)
Link
PubMed
2017
- Z. Jia, A. Beugelskijk, J. Chen, and J.D. Schmit, “The Levinthal Problem in Amyloid Aggregation: Sampling of a Flat Reaction Space”, J. Phys. Chem. B 121, 1576-1586 (2017)
Link
PubMed
- L. Zhang and J.D. Schmit, “Theory of Amyloid Fibril Nucleation from Folded Proteins”, Israel J. Chem. 57, 738-749 (2017)
Link
PubMed
2016
- L. Zhang and J.D. Schmit, “Pseudo-one-dimensional nucleation in dilute polymer solutions”, Phys. Rev. E Rapid Communication 93, 060401(R) (2016)
PDF
Link
PubMed
- S. Whitelam, Y.R. Dahal, and J.D. Schmit, “Minimal physical requirements for crystal growth self-poisoning”, J. Chem. Phys. 144, 064903 (2016)
PDF
Link
PubMed
2012-2015
- T. Miti, M. Mulaj, J.D. Schmit, and M. Muschol, “Stable, Metastable, and Kinetically Trapped Amyloid Aggregate Phases”, Biomacromolecules, 16, 326-335 (2015).
Link
PubMed
- J.D. Schmit, F. He, S. Mishra, R.R. Ketchem, C.E. Woods, and B.A. Kerwin, “Entanglement model of antibody viscosity”, J. Phys. Chem. B, 118, 5044-5049 (2014)
Link
- S. Whitelam, L.O. Hedges, and J.D. Schmit, “Self-assembly at a nonequilibrium critical point”, Phys. Rev. Lett. 112, 155504 (2014)
PDF
Link
- N. Duff, Y.R. Dahal, J.D. Schmit, and B. Peters, “Salting out the polar polymorph: Analysis by alchemical solvent transformation, J. Chem. Phys. 140, 014501 (2014)
PDF
Link
- J.D. Schmit, “Kinetic theory of amyloid fibril templating”, J. Chem. Phys. 138, 185102 (2013)
PDF
Link
- L.R. Nemzer, B.N. Flanders, J.D. Schmit, A. Chakrabarti, and C.M. Sorensen, “Ethanol shock and lysozyme aggregation”, Soft Matter 9, 2187-2196 (2013)
PDF
Link
2010-2012
- J. D. Schmit and K. Dill, “Growth rates of protein crystals”, J. Am. Chem. Soc. 134(9), 3934–3937 (2012)
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Link
Supplement
PubMed
- L. O. Narhi, J. Schmit, K. Bechtold-Peters, and D. Sharma, “Classification of protein aggregates”, J. Pharm. Sci. 101(2), 493-498 (2012)
Link
PubMed
- K. A. Dill, K. Ghosh, and J. D. Schmit, “Reply to Vazquez: Optimal density is robust to variations in calculation”, Proc. Nat. Acad. Sci. 109, E534 (2012)
Link
PubMed
- K. A. Dill, K. Ghosh, and J. D. Schmit, “Physical limits of cells and proteomes”, Proc. Nat. Acad. Sci. 108, 17876-17882 (2011)
PDF
Link
PubMed
- J. D. Schmit, S. Whitelam, and K. Dill, “Electrostatics
and aggregation: how charge can turn a crystal into a gel”, J. Chem. Phys. 135, 085103 (2011)
PDF
Link
arXiv
PubMed
- J. D. Schmit, K. Ghosh, and K. Dill, “Why do amyloid
molecules assemble into oligomers and fibrils?”,
Biophys. J.
100, 450-458 (2011)
Link
arXiv
PubMed

- J. D. Schmit and K. Dill, “The stabilities of protein
crystals”, J. Phys. Chem. B 114, 4020-4027 (2010)
PDF
Link
PubMed
Supplement
pre-2010
- J. D. Schmit, E. Kamber, and J. Kondev, “Lattice Model of Diffusion-Limited Bimolecular Chemical Reactions in Confined Environments”, Phys. Rev. Lett. 102, 218302
(2009)
PDF
Link
arXiv
- J. D. Schmit and A. J. Levine, “Statistical Model for
Intermolecular Adhesion in Conjugated
Polymers”, Phys. Rev. Lett. 100, 198303 (2008)
PDF
Link
arXiv
- A. Rahmanisisan, C. Castelnovo, J. D. Schmit, and C. Chamon, "Dynamics of single polymers under extreme confinement", J. Stat. Mech. 9, P09022 (2007)
Link
arXiv
- J. D. Schmit and A. J. Levine, “Intermolecular adhesion in conducting polymers”, Phys. Rev. E 71, 051802 (2005)
PDF
Link
arXiv
- J. Schmit, R. Menes, and P.A. Pincus, “Dielectric-induced counterion partitioning and its effect on membrane rigidity”, Phys. Rev. E 66, 061502 (2002)
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Link
articles by Jeremy Schmit on the arXiv
articles by Jeremy Schmit on the ChemRxiv
articles by Jeremy Schmit on the bioRxiv