Recent advances in the field of atom interferometry have opened the possibility of a new class of precise and accurate inertial force sensors. We have built laboratory prototypes of accelerometers, gravity gradiometers and gyroscopes based on atom interference principles which now perform at levels which compare favorably with other state-of-the-art sensors. These instruments, and their applications in science and technology, will be presented. Applications range from new measurements of G and tests of General Relativity to the development of next generation inertial navigation systems.