The talk will describe the experimental program at the Fermilab Tevatron collider, which is the world's highest energy particle accelerator. By studying high energy collisions between the fundamental constituents of matter, we are trying to answer questions not just about particle physics but about the universe. For example, why are some forces weak and others strong? What is the structure of space-time? Is the universe filled with energy? What is the dark matter that seems to be responsible for cosmic structure?